Louisville · 2021
6–7 · #46 of 130 · Power 6.15 · MRI 2.0
| Date | Opponent | Result | Expected | Perf | |
|---|---|---|---|---|---|
| 09-07 | N | Ole Miss | L 24–43 | -7.9 | -11.1 |
| 09-11 | vs | Eastern Kentucky | W 30–3 | +44.0 | -17.0 |
| 09-17 | vs | UCF | W 42–35 | +3.5 | +3.5 |
| 09-25 | at | Florida State | W 31–23 | +0.5 | +7.5 |
| 10-02 | at | Wake Forest | L 34–37 | -9.3 | +6.3 |
| 10-09 | vs | Virginia | L 33–34 | +4.5 | -5.5 |
| 10-23 | vs | Boston College | W 28–14 | +8.3 | +5.7 |
| 10-30 | at | NC State | L 13–28 | -8.9 | -6.1 |
| 11-06 | vs | Clemson | L 24–30 | -8.9 | +2.9 |
| 11-13 | vs | Syracuse | W 41–3 | +9.8 | +28.2 |
| 11-19 | at | Duke | W 62–22 | +19.3 | +20.7 |
| 11-28 | vs | Kentucky | L 21–52 | -1.6 | -29.4 |
| 12-28 | N | Air Force | L 28–31 | -1.6 | -1.4 |